This publication highlights the work of the Network for Skin Engineering and Modeling (NSEM) in advancing the field of skin tissue engineering. NSEM is a collaborative effort between researchers, clinicians, and industry partners aimed at developing innovative techniques for creating functional skin substitutes for clinical use. The publication includes a review of current skin tissue engineering methods, as well as a description of NSEM's approach, which incorporates advanced biomaterials, 3D printing, and stem cell technology. The article also discusses NSEM's ongoing projects, including the development of a full-thickness skin model for wound healing applications. Overall, the publication underscores the importance of NSEM's work in improving the lives of patients with skin injuries and disorders.