January 14th, 1 PM (CET)
Advanced ex-vivo approaches to measuring stratum corneum oxidative stress: The HLPC-TBARS-EVS Protocol.
In the field of cutaneous tissue investigation there is a need for the development of new protocols to non-invasively establish the safety and efficacy of dermocosmetics and topical products. An HPLC-TBARS-EVSC (high performance liquid chromatography–thiobarbituric acid reactive species–ex vivo stratum corneum (SC)) assay was developed for the lipid peroxidation measurement on subjects’ SC obtained by tape stripping. The protocol has been successfully applied to evaluate the efficacy of sunscreen compounds.
André Rolim Baby. Pharmacist and Biochemist. PhD in Drugs and Medicines from the Faculty of Pharmaceutical Sciences, University of São Paulo (FCF-USP). Associate Professor at the Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, with experience in the area of Cosmetic Science for over 20 years, involving teaching, research, and scientific publications. Expertise in photoprotection, technologies applied to this class of preparations, cutaneous antioxidant potential "ex vivo", safety and cosmetic efficacy related to sun protection, and development of new protocols.
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